4th Applied Genetics Workshop
Heart Health and Breast Cancer
Cape Town: 18-19 September 2009
Durban: 23 September 2009
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8h30 |
Registration |
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Prof J Schneider – Head: Department of Pathology, University of Stellenbosch and NHLS, Tygerberg |
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Prof R Erasmus – Head: Division of Chemical Pathology, University of Stellenbosch and NHLS, Tygerberg |
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Prof K Moodley – Bioethics Unit, University of Stellenbosch, Tygerberg. |
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Dr H Avenant – Blueprint Health (Pty) Ltd., Bellville |
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Jonathan O’Halloran – QuantuMDx Technologies, University of Stellenbosch, Tygerberg |
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Dr Maritha Kotze – Dept of Pathology, University of Stellenbosch, Tygerberg & Gknowmix |
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Dr Ettienne Myburgh – Private Practicing Surgeon, Panorama Hospital, Panorama |
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Prof B Mayosi – Dept of Cardiology, University of Cape Town and Grootte Schuur Hospital |
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8h30 |
Registration |
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9h00 |
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Dr Maritha Kotze – Dept of Pathology, University of Stellenbosch, Tygerberg & Gknowmix |
9h45 |
The impact of transcriptional profiling on clinical oncology: A case study presentation of breast cancer patients |
Dr Rika Pienaar – GVI Oncology, Panorama Hospital, Panorama
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10h15 |
Reimbursement of breast cancer genetic tests by medical aids |
Prof Manie de Klerk – Qualsa Managed Care, Cape Town |
11h00 |
Break |
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11h15 |
The 70-gene MammaPrint breast cancer service |
Ronald van Klaveren – Agendia, The Netherlands |
11h45 |
Application of MammaPrint in South African breast cancer patients |
Prof J Apffelstaedt– Dept of Surgery, University of Stellenbosch, Tygerberg
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12h15 |
A global view of breast cancer genetic testing |
Elaine Warburton – QuantuMDx, London, UK. |
12h45 |
Breast cancer genetic counselling |
Frieda Loubser – Registered genetic counsellor, University of Cape Town and NHLS |
13h30 |
Lunch |
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8h30 |
Registration |
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9h00 |
Introduction: Research Innovation |
Dr Tony Bunn – Innovation Centre, Medical Research Council, Tygerberg |
9h30 |
Advances in individualisation of therapeutic intent in breast cancer treatment |
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10h15 |
Ethics and genetics: Development of a web-based genetic service delivery system |
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11h00 |
Break |
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11h15 |
A global view of breast cancer genetic testing |
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11h45 |
Inclusion of ER, PR, HER2/neu and BRCA gene expression profiling as part of the 70-gene MammaPrint breast cancer service |
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12h30 |
Pocket pathology: Development of a lab-on-a-chip genetics system with applications to cardiology and cancer diagnostics |
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13h00 |
Lunch break |
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13h30 |
Breast cancer genetic testing service: BRCA1 and BRCA2 mutation detection |
Natalie Williams – Registered Medical Scientist, Molecular Diagnostic Services, Durban |
14h00 |
Application of a pathology supported nutrigenetics model in clinical practice |
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14h30 |
Application of nutritional genetics in dietetic practice |
Sarita Banitz – Registered dietician, Pretoria |
15h00 |
Closure |
Dr D York – Molecular Diagnostic Services, Durban |
This Applied Genetics Workshop aimed to improve genetic knowledge transfer between scientists, healthcare practitioners and the public. Public awareness campaigns focusing on Heart Health and Breast Cancer during the months of September and October, respectively, always spark interest in genetic risk factors. Knowledgeable clinicians play a key role in matching disease diagnosis and therapeutic design with the pathology and genetic profile of patients.
As the number of genetic tests used in disease diagnosis and intervention programs increase, the gap between genome research and clinical practice has widened. Pathology is ideally suited to provide a bridge between molecular genetics and clinical medicine. This concept termed pathology supported genetic testingTM was introduced by the Department of Pathology at
Stellenbosch University in April 2008, based on an integrated service and research approach. It provides the science behind the service offered via the Gknowmix.com genetic knowledge integration system, developed over the past two years with financial support from the Industrial Development Corporation of South Africa
Our Genetic Care Centre (www.genecare.biz) provides the infrastructure for seamless integration of the following professional activities involved in genetic testing service delivery:
- Clinicians: Patient consultation, clinical assessment and intervention
- Genetic counsellors: Genetic risk assessment and family counselling
- Laboratories: Pathology, molecular genetic testing and evaluation
- Medical scientists: Data integration, interpretation and reporting
New insights gained from the GeneTalk Workshop will guide the way during roll-out of this new genetics model in clinical practice. A synopsis of the workshop theme was provided in the workshop handout, with particular focus on the role of genetics in chronic diseases such as cardiovascular disease and lifestyle-related cancers, particularly breast cancer that may be inherited or acquired due to genetic abnormalities.
Accredited with 7 CEU’s in level 1, including 2 ethics points in level